Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mreBCell wall actin-like component MreB, Rod shaping protein; Function of strongly homologous gene; cell process. (328 aa)    
Predicted Functional Partners:
CCH88133.1
Penicillin-binding protein transpeptidase.
 
 
 0.921
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.866
tufB
Elongation factor Tu (EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.774
ftsI
Cell division protein FtsI/penicillin-binding protein 2; Function of strongly homologous gene; enzyme.
 
 
 
 0.754
tig
Peptidyl-prolyl cis/trans isomerase, Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
   0.693
pheT
Phenylalanyl-tRNA synthetase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
 
 0.684
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.666
ftsW
Cell division protein FtsW; Function of strongly homologous gene; cell process; Belongs to the SEDS family.
 
 
 0.660
pbpA
Peptidoglycan glycosyltransferase, penicillin-binding protein A; Function of strongly homologous gene; enzyme.
 
 
 
 0.640
CCH87522.1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase with a HTH repressor domain; Function of strongly homologous gene; enzyme.
 
  
 0.591
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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