STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH88226.1Putative acid phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (320 aa)    
Predicted Functional Partners:
CCH88227.1
Putative arylsulfatase, N-terminal; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.786
CCH88386.1
Arylsulfatase; Function of strongly homologous gene; enzyme.
 
     0.783
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.770
CCH89352.1
Homologs of previously reported genes of unknown function.
 
     0.748
cbs
Cystathionine beta-synthase; Function of strongly homologous gene; enzyme.
    
 0.705
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.673
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.660
CCH88441.1
Sulfatase-modifying factor; Function of strongly homologous gene; cell process.
 
     0.647
CCH88242.1
Sulfatase-modifying factor 1; Function of strongly homologous gene; factor.
 
     0.617
hisH
Imidazole glycerol phosphate synthase subunit hisH,glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.584
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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