STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH88255.1Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; Function of strongly homologous gene; enzyme. (259 aa)    
Predicted Functional Partners:
ligK
4-carboxy-4-hydroxy-2-oxoadipate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  0.991
pheB
Metapyrocatechase; Function of strongly homologous gene; enzyme.
 
   
 0.925
CCH88254.1
4-oxalomesaconate hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.914
CCH88257.1
Homologs of previously reported genes of unknown function.
 
    0.899
CCH87887.1
acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme.
 
 
 0.770
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
    
  0.762
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.729
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 
 0.720
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme.
  
 
 0.718
CCH89355.1
Acetate--CoA ligase (NDP forming); Function of strongly homologous gene; enzyme.
    
  0.704
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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