STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pheBMetapyrocatechase; Function of strongly homologous gene; enzyme. (334 aa)    
Predicted Functional Partners:
icmF
Methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.968
mutB
Methylmalonyl-CoA mutase large subunit (MCM-alpha); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.937
CCH88255.1
Beta-hydroxyacid dehydrogenase, 3-hydroxyisobutyrate dehydrogenase; Function of strongly homologous gene; enzyme.
 
   
 0.925
CCH88254.1
4-oxalomesaconate hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.892
CCH88257.1
Homologs of previously reported genes of unknown function.
 
   
 0.887
ligK
4-carboxy-4-hydroxy-2-oxoadipate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.884
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
  0.873
CCH88179.1
Flavin reductase domain protein FMN-binding; Function of strongly homologous gene; enzyme.
  
 
 0.845
CCH87887.1
acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme.
  
 
 0.823
CCH86254.1
Putative Rhodanese-related sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.784
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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