Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
catCMuconolactone Delta-isomerase; Function of strongly homologous gene; enzyme. (92 aa)    
Predicted Functional Partners:
menC
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
  
 
 0.893
CCH88275.1
Putative hydrolase or acyltransferase of alpha/beta superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.868
ligA
Protocatechuate 4,5-dioxygenase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.781
pcaC
4-carboxymuconolactone decarboxylase; Function of strongly homologous gene; enzyme.
  
 
 0.775
CCH88104.1
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
 
 0.774
ligB-2
Protocatechuate 4,5-dioxygenase, beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.717
CCH88277.1
Two component signal transduction histidine kinase; Function of strongly homologous gene; regulator.
 
     0.594
pcaH
Protocatechuate 3,4-dioxygenase beta chain; Function of strongly homologous gene; enzyme.
 
  
 0.577
pcaD
3-oxoadipate enol-lactonase; Function of strongly homologous gene; enzyme.
  
 
 0.553
scoB
3-oxoacid CoA-transferase subunit B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.545
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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