STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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Experiments
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[Homology]
Score
CCH88286.1Glycine cleavage T protein (Aminomethyl transferase); Function of strongly homologous gene; enzyme. (140 aa)    
Predicted Functional Partners:
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 0.987
CCH88287.1
Glycine cleavage T protein (Aminomethyl transferase); Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
     0.985
gcvH
Glycine cleavage system H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.889
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.826
ligA
Protocatechuate 4,5-dioxygenase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
  0.755
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.746
CCH88279.1
5,10-methylenetetrahydrofolate reductase; Function of strongly homologous gene; enzyme; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.740
CCH88257.1
Homologs of previously reported genes of unknown function.
  
  
  0.736
ligB-2
Protocatechuate 4,5-dioxygenase, beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
  0.727
CCH88314.1
Dimethylglycine oxidase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
 
 0.715
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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