Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (368 aa)    
Predicted Functional Partners:
CCH88289.1
Protein of unknown function; No homology to any previously reported sequences.
     0.985
CCH88288.1
Peptidase dimerization domain protein; Function of strongly homologous gene; enzyme.
   
 0.983
menE
2-succinylbenzoate--CoA ligase; Function of strongly homologous gene; enzyme.
 
  0.903
catC
Muconolactone Delta-isomerase; Function of strongly homologous gene; enzyme.
  
 
 0.893
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
  
 0.769
menC-2
O-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
     
 0.745
CCH87525.1
Dienelactone hydrolase-like enzyme; Function of strongly homologous gene; enzyme.
   
 
  0.744
CCH89298.1
Putative carboxymethylenebutenolidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
  0.744
pcaG
Protocatechuate 3,4-dioxygenase alpha chain; Function of strongly homologous gene; enzyme.
  
 
 0.634
CCH88287.1
Glycine cleavage T protein (Aminomethyl transferase); Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
       0.517
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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