| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH88120.1 | aroB | MODMU_2691 | MODMU_3332 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.690 |
| CCH88120.1 | aroQ | MODMU_2691 | MODMU_2943 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. | 3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.631 |
| CCH88372.1 | CCH88374.1 | MODMU_2944 | MODMU_2946 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Homologs of previously reported genes of unknown function. | 0.785 |
| CCH88372.1 | aroE | MODMU_2944 | MODMU_2945 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.991 |
| CCH88372.1 | aroE-2 | MODMU_2944 | MODMU_3336 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Shikimate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the shikimate dehydrogenase family. | 0.772 |
| CCH88372.1 | aroQ | MODMU_2944 | MODMU_2943 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.900 |
| CCH88372.1 | entC | MODMU_2944 | MODMU_4975 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Isochorismate synthase; Function of strongly homologous gene; enzyme. | 0.789 |
| CCH88372.1 | trpE | MODMU_2944 | MODMU_3409 | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.766 |
| CCH88374.1 | CCH88372.1 | MODMU_2946 | MODMU_2944 | Homologs of previously reported genes of unknown function. | Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.785 |
| CCH88374.1 | aroE | MODMU_2946 | MODMU_2945 | Homologs of previously reported genes of unknown function. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.796 |
| CCH88374.1 | aroQ | MODMU_2946 | MODMU_2943 | Homologs of previously reported genes of unknown function. | 3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.698 |
| aroA | aroB | MODMU_4594 | MODMU_3332 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.997 |
| aroA | aroE | MODMU_4594 | MODMU_2945 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.917 |
| aroA | aroE-2 | MODMU_4594 | MODMU_3336 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the shikimate dehydrogenase family. | 0.994 |
| aroA | aroK | MODMU_4594 | MODMU_3333 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.993 |
| aroA | aroQ | MODMU_4594 | MODMU_2943 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.570 |
| aroA | entC | MODMU_4594 | MODMU_4975 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Isochorismate synthase; Function of strongly homologous gene; enzyme. | 0.579 |
| aroA | trpE | MODMU_4594 | MODMU_3409 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.401 |
| aroB | CCH88120.1 | MODMU_3332 | MODMU_2691 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family. | 0.690 |
| aroB | aroA | MODMU_3332 | MODMU_4594 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.997 |
