STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH88372.1Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (608 aa)    
Predicted Functional Partners:
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.991
icmF
Methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.932
CCH87887.1
acetyl-CoA carboxylase, biotin carboxylase subunit; Function of strongly homologous gene; enzyme.
  
 
 0.920
CCH88375.1
Transcriptional regulator, TetR family; Function of strongly homologous gene; factor.
 
     0.918
aroQ
3-dehydroquinate dehydratase 1; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
    
 0.900
hmgA
Homogentisate 1,2-dioxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.894
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
    
 0.836
panE
2-dehydropantoate 2-reductase; Function of strongly homologous gene; enzyme.
  
    0.830
accC
Carbamoyl-phosphate synthase L chain ATP-binding protein; Function of strongly homologous gene; enzyme.
  
 
 0.816
pab
Para-aminobenzoate synthase; Function of strongly homologous gene; enzyme.
  
 
 0.806
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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