STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
soxA-2Sarcosine oxidase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (960 aa)    
Predicted Functional Partners:
soxD-2
Sarcosine oxidase subunit delta; Function of strongly homologous gene; enzyme.
 0.999
soxD
Sarcosine oxidase delta subunit; Function of strongly homologous gene; enzyme.
 0.998
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 0.997
soxG-2
Sarcosine oxidase subunit gamma; Function of strongly homologous gene; enzyme.
 0.997
soxB-2
Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.994
soxG
Sarcosine oxidase gamma subunit; Function of strongly homologous gene; enzyme.
 
 0.983
soxB
Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.983
CCH88495.1
Creatinase; Function of strongly homologous gene; enzyme.
 
 0.973
CCH88314.1
Dimethylglycine oxidase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
 
0.945
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.936
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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