STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CCH88502.1Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa)    
Predicted Functional Partners:
CCH88503.1
Protein of unknown function; No homology to any previously reported sequences.
 
 
 0.981
pyc
Pyruvate carboxylase; Function of strongly homologous gene; enzyme.
 
 
 0.981
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.980
accD-2
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme.
 
 
 0.970
fabD-2
Malonyl CoA-acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.969
CCH85681.1
NAD-dependent malic enzyme; Function of strongly homologous gene; enzyme.
   
 0.925
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
  0.920
accB
Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.916
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
  
 
 0.916
citA
Citrate synthase 2; Function of strongly homologous gene; enzyme; Belongs to the citrate synthase family.
  
 0.915
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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