STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CCH88502.1Pyruvate carboxylase (fragment); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1117 aa)    
Predicted Functional Partners:
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.996
accD-2
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme.
  
 0.993
fabD-2
Malonyl CoA-acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.989
CCH88503.1
Protein of unknown function; No homology to any previously reported sequences.
 
 0.986
pyc
Pyruvate carboxylase; Function of strongly homologous gene; enzyme.
 
 0.986
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.938
ahs
Allophanate hydrolase, subunit2; Function of strongly homologous gene; enzyme.
   
  0.934
accB
Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 0.929
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
  0.832
ribD-2
Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.811
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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