STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaG-3DNA primase; Function of strongly homologous gene; enzyme. (1844 aa)    
Predicted Functional Partners:
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
 
 0.951
dnaB
Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 0.938
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.830
CCH87131.1
Homologs of previously reported genes of unknown function.
 
   
 0.813
CCH88529.1
Homologs of previously reported genes of unknown function.
 
   
 0.812
CCH89134.1
Homologs of previously reported genes of unknown function.
 
   
 0.812
CCH87133.1
Homologs of previously reported genes of unknown function.
 
   
 0.804
CCH88524.1
Putative conjugative transfer gene complex protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process.
 
   
 0.804
CCH89129.1
Type IV secretory pathway VirD4-like; Function of strongly homologous gene; cell process.
 
   
 0.804
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.786
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.