STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH88544.12,5-didehydrogluconate reductase; Function of strongly homologous gene; enzyme. (292 aa)    
Predicted Functional Partners:
CCH88542.1
Homologs of previously reported genes of unknown function.
     0.903
CCH88543.1
Short-chain dehydrogenase/reductase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.779
CCH88540.1
Major facilitator superfamily MFS_1; Function of strongly homologous gene; transporter.
       0.581
CCH88541.1
Protein of unknown function; No homology to any previously reported sequences.
       0.581
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.539
CCH88545.1
Transcriptional regulator (fragment); Function of strongly homologous gene; regulator.
  
    0.522
CCH88546.1
Transcriptional regulator, XRE family; Function of strongly homologous gene; regulator.
  
    0.522
CCH85610.1
Polyketide beta-ketoacyl synthase 2; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
     
  0.499
CCH88538.1
NAD-dependent epimerase/dehydratase; Function of strongly homologous gene; enzyme.
  
   0.473
CCH85581.1
Putative NADP-dependent oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.422
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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