STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH88643.1Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. (393 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.994
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.989
cysG
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
 
 
 0.980
hemD
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
 
 
 0.957
CCH88646.1
Major facilitator superfamily MFS_1 (Nitrate/nitrite transporter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
 
  
 0.883
hemB
Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family.
  
 
 0.840
CCH89435.1
Two-component sensor histidine kinase; Function of strongly homologous gene; enzyme.
  
 
 0.735
CCH89003.1
Putative Sirohydrochlorin cobaltochelatase domains, cbiX family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.727
CCH90658.1
Sensor protein with an histidine kinase signal transduction domain; Function of strongly homologous gene; regulator.
  
 
 0.711
nasC
Assimilatory nitrate reductase catalytic subunit; Function of strongly homologous gene; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.703
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.