| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCH85814.1 | CCH88680.1 | MODMU_0356 | MODMU_3267 | Putative Riboflavin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.529 |
| CCH85814.1 | thyA | MODMU_0356 | MODMU_4341 | Putative Riboflavin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.474 |
| CCH87014.1 | CCH88680.1 | MODMU_1569 | MODMU_3267 | Bifunctional deaminase-reductase; Function of strongly homologous gene; enzyme. | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.771 |
| CCH87014.1 | thyA | MODMU_1569 | MODMU_4341 | Bifunctional deaminase-reductase; Function of strongly homologous gene; enzyme. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.474 |
| CCH88678.1 | CCH88679.1 | MODMU_3265 | MODMU_3266 | Transcriptional regulator, XRE family; Function of strongly homologous gene; putative regulator. | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.889 |
| CCH88678.1 | CCH88680.1 | MODMU_3265 | MODMU_3267 | Transcriptional regulator, XRE family; Function of strongly homologous gene; putative regulator. | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.479 |
| CCH88679.1 | CCH88678.1 | MODMU_3266 | MODMU_3265 | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Transcriptional regulator, XRE family; Function of strongly homologous gene; putative regulator. | 0.889 |
| CCH88679.1 | CCH88680.1 | MODMU_3266 | MODMU_3267 | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.594 |
| CCH88679.1 | CCH88681.1 | MODMU_3266 | MODMU_3268 | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Abortive infection protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. | 0.432 |
| CCH88680.1 | CCH85814.1 | MODMU_3267 | MODMU_0356 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Riboflavin biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.529 |
| CCH88680.1 | CCH87014.1 | MODMU_3267 | MODMU_1569 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional deaminase-reductase; Function of strongly homologous gene; enzyme. | 0.771 |
| CCH88680.1 | CCH88678.1 | MODMU_3267 | MODMU_3265 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Transcriptional regulator, XRE family; Function of strongly homologous gene; putative regulator. | 0.479 |
| CCH88680.1 | CCH88679.1 | MODMU_3267 | MODMU_3266 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.594 |
| CCH88680.1 | CCH88681.1 | MODMU_3267 | MODMU_3268 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Abortive infection protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. | 0.581 |
| CCH88680.1 | CCH88682.1 | MODMU_3267 | MODMU_3269 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glyoxalase/bleomycin resistance protein/dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.516 |
| CCH88680.1 | CCH90122.1 | MODMU_3267 | MODMU_4741 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional deaminase-reductase domain protein; Function of strongly homologous gene; enzyme. | 0.756 |
| CCH88680.1 | CCH90750.1 | MODMU_3267 | MODMU_5376 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Homologs of previously reported genes of unknown function. | 0.624 |
| CCH88680.1 | ribD | MODMU_3267 | MODMU_3166 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Riboflavin biosynthesis protein ribD; Function of strongly homologous gene; enzyme. | 0.598 |
| CCH88680.1 | thyA | MODMU_3267 | MODMU_4341 | Bifunctional deaminase-reductase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.474 |
| CCH88681.1 | CCH88679.1 | MODMU_3268 | MODMU_3266 | Abortive infection protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. | Putative isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.432 |