STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citA-2Citrate synthase; Function of strongly homologous gene; enzyme. (323 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.986
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.977
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 
 0.974
pdhC
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; Function of strongly homologous gene; enzyme.
  
 0.950
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.946
CCH88131.1
Butyrate--CoA ligase; Function of strongly homologous gene; enzyme.
  
 0.946
CCH88796.1
Putative Extradiol ring-cleavage dioxygenase class III protein subunit B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.946
aceB
Malate synthase; Function of strongly homologous gene; enzyme.
   
 0.942
aceB-2
Malate synthase; Function of strongly homologous gene; enzyme; Belongs to the malate synthase family.
   
 0.942
mqo
Malate:quinone oxidoreductase; Function of strongly homologous gene; enzyme.
  
 
 0.940
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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