STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaEDNA polymerase III subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1180 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.990
CCH87179.1
DNA polymerase III, delta subunit; Function of strongly homologous gene; enzyme.
 
 0.986
dnaX-2
DNA polymerase III, delta prime subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.982
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.980
polC
DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.953
CCH89510.1
Putative exonuclease, RNase T and DNA polymerase III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.946
CCH89124.1
Protein of unknown function; No homology to any previously reported sequences.
   
 0.918
ssb-3
Single-stranded DNA-binding protein; Function of strongly homologous gene; cell process.
 
 
 0.815
gyrA
DNA gyrase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.762
ssb
Single-stranded DNA-binding protein; Function of strongly homologous gene; cell process.
   
 0.744
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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