STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mraZPutative protein mraZ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative cell process; Belongs to the MraZ family. (144 aa)    
Predicted Functional Partners:
mraW
S-adenosyl-dependent methyl transferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
 
  
 0.979
ftsI
Cell division protein FtsI/penicillin-binding protein 2; Function of strongly homologous gene; enzyme.
 
  
 0.786
ftsZ
Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
  
 0.722
ftsK
DNA translocase ftsK; Function of strongly homologous gene; cell process.
 
  
 0.699
murF
UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 
 0.671
ftsQ
Membrane anchored protein involved in growth of wall at septum; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
 
   
 0.659
ftsW
Cell division protein FtsW; Function of strongly homologous gene; cell process; Belongs to the SEDS family.
 
  
 0.659
CCH88133.1
Penicillin-binding protein transpeptidase.
  
  
 0.639
pheT
Phenylalanyl-tRNA synthetase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
   
   0.617
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
     
 0.600
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.