Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH88883.1Methyltransferase type 12; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (204 aa)    
Predicted Functional Partners:
CCH88884.1
N-acetylglucosaminyl phosphatidylinositol deacetylase; Function of strongly homologous gene; enzyme.
     0.994
CCH88885.1
Putative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     0.982
CCH88882.1
Glycosyl transferase family 2 (fragment); Function of strongly homologous gene; enzyme.
 
    0.947
CCH88314.1
Dimethylglycine oxidase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
    
  0.809
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.784
CCH88886.1
Protein of unknown function; No homology to any previously reported sequences.
       0.773
CCH88157.1
Phthalate 4,5-dioxygenase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the cytochrome P450 family.
    
 0.664
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.618
soxA
Sarcosine oxidase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.605
CCH88887.1
Homologs of previously reported genes of unknown function.
       0.565
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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