Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HaoHydroxyacid oxidase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (385 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
  
 
 0.773
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
    
 0.759
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.689
CCH90543.1
Serine-glyoxylate aminotransferase; Function of strongly homologous gene; enzyme.
  
 0.640
CCH89612.1
Endonuclease/exonuclease/phosphatase; Function of strongly homologous gene; enzyme.
     
  0.637
CCH87716.1
FAD/FMN-dependent dehydrogenase; Function of strongly homologous gene; enzyme.
  
 0.632
CCH90542.1
D-lactate dehydrogenase (cytochrome); Function of strongly homologous gene; enzyme.
  
 0.632
lutP
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.590
CCH88915.1
Transcriptional regulator; Function of strongly homologous gene; regulator.
       0.569
CCH88913.1
Lycopene cyclase domain protein; Function of strongly homologous gene; enzyme.
       0.565
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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