STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ltaAL-allo-threonine aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (348 aa)    
Predicted Functional Partners:
gcvP
Glycine cleavage system P-protein (glycine dehydrogenase); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.900
engD
GTP-dependent nucleic acid-binding protein (engD); ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
      0.851
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.833
aroF
Phospho-2-dehydro-3-deoxyheptonate aldolase; Function of strongly homologous gene; enzyme; Belongs to the class-II DAHP synthase family.
       0.800
thrC-2
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.750
thrC
L-threonine synthase; Function of strongly homologous gene; enzyme.
   
 0.737
CCH88314.1
Dimethylglycine oxidase; Function of strongly homologous gene; enzyme; Belongs to the GcvT family.
   
 0.691
soxA
Sarcosine oxidase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.680
CCH90543.1
Serine-glyoxylate aminotransferase; Function of strongly homologous gene; enzyme.
    
 0.663
CCH89434.1
Thioredoxin reductase (NADPH); Function of strongly homologous gene; enzyme.
    
  0.640
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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