Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroFPhospho-2-dehydro-3-deoxyheptonate aldolase; Function of strongly homologous gene; enzyme; Belongs to the class-II DAHP synthase family. (445 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.979
CCH90223.1
Monofunctional chorismate mutase; Function of strongly homologous gene; enzyme.
   
 0.957
aroG
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.915
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
    
 0.844
ltaA
L-allo-threonine aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.800
tkt
Transketolase; Function of strongly homologous gene; enzyme; Belongs to the transketolase family.
     
 0.787
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
     
  0.756
CCH88336.1
Transketolase C-terminal section; Function of strongly homologous gene; enzyme.
     
  0.741
CCH88337.1
Transketolase N-terminal section (TK); Function of strongly homologous gene; enzyme.
     
  0.741
talB
Transaldolase; Function of strongly homologous gene; enzyme.
    
 0.637
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.