STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
sucBDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Function of strongly homologous gene; enzyme. (623 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.997
bfmBC
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.994
aceE
Fragment of conserved protein of unknown function (part 1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.991
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
 
0.989
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.989
CCH87101.1
Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.987
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
  
 0.971
citA
Citrate synthase 2; Function of strongly homologous gene; enzyme; Belongs to the citrate synthase family.
  
 0.962
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.961
lpdA
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component; Function of strongly homologous gene; enzyme.
 0.960
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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