STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CCH88999.1Silent information regulator protein Sir2; Function of homologous gene experimentally demonstrated in an other organism; regulator. (244 aa)    
Predicted Functional Partners:
nadE-2
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.923
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.919
pncA
Nicotinamidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.906
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
   
  0.906
punA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.906
CCH89000.1
Phosphoesterase, PA-phosphatase related; Function of strongly homologous gene; enzyme.
       0.773
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
 
 0.769
CCH89774.1
Cell envelope-related function transcriptional attenuator common domain; Function of strongly homologous gene; regulator.
   
    0.723
CCH86023.1
Transcriptional regulator, HxlR family; Function of strongly homologous gene; regulator.
  
    0.715
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.703
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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