Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apeHDipeptidyl aminopeptidase/acylaminoacyl peptidase; Function of strongly homologous gene; enzyme. (685 aa)    
Predicted Functional Partners:
CCH89061.1
Protein of unknown function; No homology to any previously reported sequences.
 
     0.811
lldD-2
L-lactate dehydrogenase [cytochrome] 2; Function of strongly homologous gene; enzyme.
  
    0.734
amdA-3
Acetamidase/formamidase; Function of strongly homologous gene; enzyme.
       0.636
CCH89058.1
3-ketoacyl-CoA reductase; Function of strongly homologous gene; enzyme.
       0.623
CCH89063.1
Putative Imidazolonepropionase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.618
CCH89686.1
Transcriptional regulator, ArsR family; Function of strongly homologous gene; regulator.
  
    0.586
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
    
  0.583
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.550
CCH85553.1
Gamma-glutamyltranspeptidase; Function of strongly homologous gene; enzyme.
  
   
 0.527
CCH85747.1
IMP dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
  0.527
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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