STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribD-3Riboflavin biosynthesis protein; Function of strongly homologous gene; enzyme. (246 aa)    
Predicted Functional Partners:
ribBA
Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 
 0.949
ribE
Riboflavin synthase alpha chain; Function of strongly homologous gene; enzyme.
 
  
 0.873
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.839
treZ
Malto-oligosyltrehalose trehalohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.814
ribF
Riboflavin biosynthesis protein ribF [Includes: Riboflavin kinase; Function of strongly homologous gene; enzyme; Belongs to the ribF family.
  
  
 0.736
folC
Folylpolyglutamate synthase/dihydrofolate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family.
     
 0.639
CCH89073.1
Short-chain dehydrogenase/reductase (SDR) family protein; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.539
cofD
LPPG:FO 2-phospho-L-lactate transferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.528
CCH89074.1
Putative L-xylulose reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.506
folP
Dihydropteroate synthase 2; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
   
 0.492
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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