STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89086.1Putative DNA polymerase LigD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (355 aa)    
Predicted Functional Partners:
lig
ATP-dependent DNA ligase; Function of strongly homologous gene; enzyme.
   
 0.992
CCH87510.1
DNA polymerase LigD, ligase domain protein; Function of strongly homologous gene; enzyme.
   
 0.979
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.906
ligB
ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.812
xthA
Exodeoxyribonuclease III; Function of strongly homologous gene; enzyme.
 
    0.696
CCH89087.1
Putative Tyrosine recombinase xerC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 'phage' integrase family.
       0.601
CCH89085.1
Putative Serine-type D-Ala-D-Ala carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.533
mutM
DNA-(Apurinic or apyrimidinic site) lyase; Function of strongly homologous gene; enzyme; Belongs to the FPG family.
 
     0.532
CCH89084.1
Alpha/beta hydrolase; Function of strongly homologous gene; enzyme.
       0.496
CCH88046.1
5'-3' exonuclease; Function of strongly homologous gene; enzyme.
  
   
 0.408
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.