STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
guaDGuanine deaminase; Function of strongly homologous gene; enzyme. (185 aa)    
Predicted Functional Partners:
CCH86941.1
Amidohydrolase; Function of strongly homologous gene; enzyme.
  
     0.769
CCH86947.1
5-methylthioadenosine/S-adenosylhomocysteine deaminase; Function of strongly homologous gene; enzyme.
  
     0.767
yedX
5-hydroxyisourate hydrolase; Function of strongly homologous gene; enzyme; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.631
CCH88799.1
Putative Hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
  0.520
punA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
 
 
 0.508
uox
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.486
rihC
Non-specific ribonucleoside hydrolase rihC; Function of strongly homologous gene; enzyme.
 
 
 0.485
ahcY
Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
  0.422
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.411
xdhC-2
Xanthine dehydrogenase, small subunit, 2Fe-2S ferredoxin, iron-sulphur binding; Function of strongly homologous gene; enzyme.
  
 
 0.406
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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