STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrBPeptide methionine sulfoxide reductase msrB; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the MsrB Met sulfoxide reductase family. (139 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.995
CCH85840.1
Homologs of previously reported genes of unknown function.
 
      0.707
grpE
Molecular chaperone GrpE (Heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
   
 
 0.622
CCH89306.1
Exported protein of unknown function; No homology to any previously reported sequences.
       0.608
trxB
Two component thioredoxin reductase carring response regulator; Function of strongly homologous gene; enzyme.
  
  
 0.550
nudC
NADH pyrophosphatase; Function of strongly homologous gene; enzyme; Belongs to the Nudix hydrolase family.
 
      0.534
rpmJ
50S ribosomal protein L36; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL36 family.
    
 
 0.509
katE
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.484
katA-2
Catalase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the catalase family.
   
  
 0.484
CCH90667.1
Putative glutathione peroxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutathione peroxidase family.
  
  
 0.474
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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