STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psuGIndigoidine synthase A; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (319 aa)    
Predicted Functional Partners:
punA
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
  0.909
upp
Uracil phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UPRTase family.
    
  0.907
pyrR
Bifunctional protein pyrR [Includes: Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.904
deoA
Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.903
codA
Cytosine deaminase; Function of strongly homologous gene; enzyme.
     
  0.900
CCH88700.1
Putative cytosine deaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
cdd
Cytosine deaminase; Function of strongly homologous gene; enzyme.
     
  0.900
scrK
Fructokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.885
apeB
Aminopeptidase, M18 family; Function of strongly homologous gene; enzyme.
 
      0.648
CCH89341.1
Homologs of previously reported genes of unknown function.
       0.638
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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