STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89345.1Homologs of previously reported genes of unknown function. (197 aa)    
Predicted Functional Partners:
CCH89481.1
Homologs of previously reported genes of unknown function.
  
 0.590
CCH89508.1
Endonuclease/exonuclease/phosphatase.
  
 0.590
xthA
Exodeoxyribonuclease III; Function of strongly homologous gene; enzyme.
  
 0.590
lig
ATP-dependent DNA ligase; Function of strongly homologous gene; enzyme.
 
   
 0.573
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.546
nfo
Endonuclease IV with intrinsic 3'-5' exonuclease activity; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.544
nfo-2
Endonuclease 4; Function of strongly homologous gene; enzyme.
  
 
 0.544
CCH88046.1
5'-3' exonuclease; Function of strongly homologous gene; enzyme.
 
 
 
 0.495
CCH89344.1
Homologs of previously reported genes of unknown function.
       0.477
CCH88831.1
Putative HNH endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.455
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.