STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89355.1Acetate--CoA ligase (NDP forming); Function of strongly homologous gene; enzyme. (902 aa)    
Predicted Functional Partners:
acuC
Acetoin dehydrogenase; Function of strongly homologous gene; enzyme.
 
     0.934
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
 0.815
CCH86358.1
Transcriptional regulator, DeoR family; Function of strongly homologous gene; regulator.
    
   0.691
CCH87478.1
Transcriptional regulator, DeoR family; Function of strongly homologous gene; regulator.
    
   0.691
CCH90606.1
Transcriptional regulator, DeoR family; Function of strongly homologous gene; factor.
    
   0.691
CCH90844.1
Putative transcriptional regulator, DeoR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
    
   0.691
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
 
    0.652
ideR
Iron-dependent repressor ideR; Function of strongly homologous gene; regulator.
       0.638
CCH85874.1
Acetoacetyl-CoA synthase; Function of strongly homologous gene; enzyme.
 
  
 0.586
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.537
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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