STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panE2-dehydropantoate 2-reductase; Function of strongly homologous gene; enzyme. (317 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
    
 0.941
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.940
CCH88288.1
Peptidase dimerization domain protein; Function of strongly homologous gene; enzyme.
 
    
 0.902
CCH89421.1
Short-chain dehydrogenase/reductase SDR; Function of strongly homologous gene; enzyme.
 
     0.806
CCH88372.1
Putative 4-hydroxyphenylpyruvate dioxygenase containing a TIM-barrel fold (N-ter); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.805
CCH89420.1
Homologs of previously reported genes of unknown function.
       0.782
pip-3
Proline iminopeptidase; Function of strongly homologous gene; enzyme.
  
    0.774
CCH85654.1
Alkylated DNA repair protein, DNA-N1-methyladenine dioxygenase; Function of strongly homologous gene; enzyme.
   
    0.771
CCH89414.1
Zn-dependent dipeptidase microsomal dipeptidase; Function of strongly homologous gene; enzyme.
 
     0.735
CCH89415.1
Putative peptidase M20; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.713
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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