STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CCH89435.1Two-component sensor histidine kinase; Function of strongly homologous gene; enzyme. (476 aa)    
Predicted Functional Partners:
CCH89434.1
Thioredoxin reductase (NADPH); Function of strongly homologous gene; enzyme.
 
 0.996
trxB
Two component thioredoxin reductase carring response regulator; Function of strongly homologous gene; enzyme.
 
 0.953
CCH90658.1
Sensor protein with an histidine kinase signal transduction domain; Function of strongly homologous gene; regulator.
 
 0.950
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.948
CCH87489.1
Putative CyaI3 adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 0.946
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 0.943
ribBA
Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 0.924
CCH87231.1
Adenylyl cyclase; Function of strongly homologous gene; enzyme.
  
 0.917
CCH89349.1
Adenylate/guanylate cyclase; Function of strongly homologous gene; enzyme.
  
 0.917
pdhB
Pyruvate dehydrogenase E1 component subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.894
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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