STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89510.1Putative exonuclease, RNase T and DNA polymerase III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (428 aa)    
Predicted Functional Partners:
polC
DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
0.986
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.984
dnaE
DNA polymerase III subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.977
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.973
dnaX-2
DNA polymerase III, delta prime subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.973
CCH87179.1
DNA polymerase III, delta subunit; Function of strongly homologous gene; enzyme.
    
 0.960
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
 
 0.948
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.915
uvrD-2
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme; Belongs to the helicase family. UvrD subfamily.
  
  
 0.879
pcrA
ATP-dependent DNA helicase pcrA; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.879
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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