Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH89532.1N-6 DNA methylase; Function of strongly homologous gene; enzyme. (486 aa)    
Predicted Functional Partners:
CCH89531.1
Type-1 restriction enzyme StySPI; Function of strongly homologous gene; enzyme.
 
 
 0.999
CCH89530.1
Type III restriction enzyme, restriction (R) subunit; Function of strongly homologous gene; enzyme.
 
 
 0.990
CCH89406.1
Protein of unknown function, putative recB domain; No homology to any previously reported sequences.
  
  
 0.717
CCH89444.1
Putative DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.569
CCH89536.1
Homologs of previously reported genes of unknown function.
  
  
 0.563
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
     
 0.556
CCH88956.1
Homologs of previously reported genes of unknown function.
  
  
 0.555
CCH85634.1
Protein of unknown function; No homology to any previously reported sequences.
       0.527
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
   
 
 0.487
cbs
Cystathionine beta-synthase; Function of strongly homologous gene; enzyme.
  
  
 0.469
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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