STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89532.1N-6 DNA methylase; Function of strongly homologous gene; enzyme. (486 aa)    
Predicted Functional Partners:
CCH89531.1
Type-1 restriction enzyme StySPI; Function of strongly homologous gene; enzyme.
 
 
 0.999
CCH89530.1
Type III restriction enzyme, restriction (R) subunit; Function of strongly homologous gene; enzyme.
 
 
 0.991
CCH89406.1
Protein of unknown function, putative recB domain; No homology to any previously reported sequences.
  
  
 0.661
CCH88956.1
Homologs of previously reported genes of unknown function.
  
  
 0.582
CCH85807.1
Protein of unknown function; No homology to any previously reported sequences.
  
  
 0.561
CCH89444.1
Putative DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.553
CCH89536.1
Homologs of previously reported genes of unknown function.
  
  
 0.538
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
   
 
 0.510
guaA
GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.
     
 0.474
CCH89529.1
Protein of unknown function; No homology to any previously reported sequences.
       0.460
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.