STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sacIMModification methylase SacI; Function of strongly homologous gene; enzyme. (355 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase 1 (AdoMet synthetase); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.925
ahcY
Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.909
CCH86170.1
Homologs of previously reported genes of unknown function.
     
  0.900
vsr-3
DNA mismatch endonuclease Vsr; Function of strongly homologous gene; enzyme.
 
   
 0.718
CCH89538.1
Putative type II restriction endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.697
dnaG
DNA primase; Function of strongly homologous gene; enzyme.
  
  
 0.534
dnaG-3
DNA primase; Function of strongly homologous gene; enzyme.
  
  
 0.534
dnaG-4
DNA primase; Function of strongly homologous gene; enzyme.
  
  
 0.534
CCH85886.1
Membrane-bound metal-dependent hydrolase; Function of strongly homologous gene; enzyme.
   
    0.435
CCH89953.1
Homologs of previously reported genes of unknown function.
   
    0.435
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.