Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CCH89662.1Aldehyde dehydrogenase [NAD+]; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (486 aa)    
Predicted Functional Partners:
aldH
NAD-dependent aldehyde dehydrogenase; Function of strongly homologous gene; enzyme.
 
     0.956
CCH86880.1
Proline dehydrogenase; Function of strongly homologous gene; enzyme.
 
 0.922
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.866
CCH88052.1
2-keto-3-deoxy-L-rhamnonate aldolase; Function of strongly homologous gene; enzyme; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.815
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
  
 0.806
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
   
 0.785
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.782
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 0.777
sdhA
Succinate dehydrogenase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.776
icd
Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.758
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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