STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
CCH89711.1Putative ATP-dependent helicase lhr; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1532 aa)    
Predicted Functional Partners:
CCH89713.1
DNA glycosylase; Function of strongly homologous gene; enzyme.
  
 0.879
CCH89714.1
DNA glycosylase; Function of strongly homologous gene; enzyme.
  
 0.878
radA
DNA repair protein radA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.708
CCH86342.1
DNA glycosylase; Function of strongly homologous gene; enzyme; Belongs to the FPG family.
  
  
 0.666
polC
DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
    0.548
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
  
 0.541
CCH89710.1
Homologs of previously reported genes of unknown function.
       0.540
mutM
DNA-(Apurinic or apyrimidinic site) lyase; Function of strongly homologous gene; enzyme; Belongs to the FPG family.
  
  
 0.520
mutM-2
Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.520
CCH90090.1
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Function of strongly homologous gene; enzyme.
 
  
 0.519
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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