STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CCH89711.1Putative ATP-dependent helicase lhr; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1532 aa)    
Predicted Functional Partners:
CCH89713.1
DNA glycosylase; Function of strongly homologous gene; enzyme.
  
 0.898
CCH89714.1
DNA glycosylase; Function of strongly homologous gene; enzyme.
  
 0.897
radA
DNA repair protein radA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.731
CCH86342.1
DNA glycosylase; Function of strongly homologous gene; enzyme; Belongs to the FPG family.
  
  
 0.648
recA
Recombinase A (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.607
polC
DNA-directed DNA polymerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
    0.554
CCH89710.1
Homologs of previously reported genes of unknown function.
       0.540
CCH90090.1
3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Function of strongly homologous gene; enzyme.
 
  
 0.522
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
  
  
 0.516
CCH89709.1
Protein of unknown function; No homology to any previously reported sequences.
       0.492
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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