STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89791.1DNA protecting protein DprA; Function of strongly homologous gene; structure. (402 aa)    
Predicted Functional Partners:
CCH89792.1
Magnesium-chelatase (Mg-protoporphyrin IX chelatase); Function of strongly homologous gene; carrier.
 
 0.972
CCH89793.1
Putative endonuclease related to Holliday junction resolvase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0102 family.
 
    0.902
CCH87178.1
ComEC/Rec2-related protein (modular protein); Function of strongly homologous gene; cell process.
 
  
 0.817
CCH90066.1
Predicted amidophosphoribosyltransferase; Function of strongly homologous gene; carrier.
 
 
 0.765
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 0.620
mtrB
Two component sensor histidine kinase mtrB; Function of strongly homologous gene; enzyme.
 
    0.585
murF
UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
     0.575
uvrD
DNA/RNA helicase, superfamily I; Function of strongly homologous gene; enzyme.
 
  
 0.558
CCH89794.1
Homologs of previously reported genes of unknown function.
       0.556
CCH88748.1
Peptidase A24A prepilin type IV; Function of strongly homologous gene; enzyme.
 
  
 0.538
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.