Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
amtBAmmonium transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter. (449 aa)    
Predicted Functional Partners:
glnK
Nitrogen regulatory protein P-II 1; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
 0.999
gltB
Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.957
glnD
[Protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.874
CCH89092.1
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
      0.742
CCH85669.1
Diguanylate cyclase/phosphodiesterase (fragment); Function of strongly homologous gene; enzyme.
 
      0.738
CCH85821.1
Diguanylate cyclase; Function of strongly homologous gene; enzyme.
 
      0.690
glnA-3
Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.689
CCH90658.1
Sensor protein with an histidine kinase signal transduction domain; Function of strongly homologous gene; regulator.
  
 0.689
glnA
Glutamine synthetase 2; Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family.
  
  
 0.666
CCH90420.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); Function of strongly homologous gene; receptor.
      0.666
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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