STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
serA-2D-3-phosphoglycerate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.950
korA
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
 0.809
CCH86438.1
L-threonine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.797
sucA
2-oxoglutarate decarboxylase; Function of strongly homologous gene; enzyme.
   
 
 0.793
CCH90543.1
Serine-glyoxylate aminotransferase; Function of strongly homologous gene; enzyme.
  
 
 0.789
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.762
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.755
CCH86105.1
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.716
glxK
Glycerate kinase; Function of strongly homologous gene; enzyme; Belongs to the glycerate kinase type-1 family.
    
  0.714
CCH86220.1
Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
  0.707
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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