STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH89903.1acetyl-CoA acetyltransferase; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)    
Predicted Functional Partners:
mmgB
3-hydroxybutyryl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
 0.987
CCH89317.1
3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; Function of strongly homologous gene; enzyme.
 0.987
CCH89910.1
3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
 0.982
CCH85874.1
Acetoacetyl-CoA synthase; Function of strongly homologous gene; enzyme.
  
 
 0.940
CCH85783.1
Acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
  
 0.938
CCH89626.1
Putative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.938
CCH90837.1
Putative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.938
CCH88131.1
Butyrate--CoA ligase; Function of strongly homologous gene; enzyme.
  
 
 0.931
acsA
Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.930
acsA-2
Acetoacetyl-coenzyme A synthetase; Function of strongly homologous gene; enzyme.
  
 
 0.930
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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