node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCH87902.1 | CCH90608.1 | MODMU_2473 | MODMU_5233 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | 0.947 |
CCH87902.1 | frk | MODMU_2473 | MODMU_2210 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | Sugar kinase, ribokinase; Function of strongly homologous gene; enzyme. | 0.915 |
CCH87902.1 | glmS | MODMU_2473 | MODMU_4874 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.911 |
CCH87902.1 | glpX | MODMU_2473 | MODMU_1056 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | Fructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.908 |
CCH87902.1 | manA-2 | MODMU_2473 | MODMU_4690 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | Mannose-6-phosphate isomerase, class I; Function of strongly homologous gene; enzyme. | 0.921 |
CCH87902.1 | pfkA | MODMU_2473 | MODMU_0037 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.916 |
CCH87902.1 | pfkA-2 | MODMU_2473 | MODMU_3509 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.916 |
CCH87902.1 | pgi | MODMU_2473 | MODMU_4321 | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | Glucose-6-phosphate isomerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. | 0.917 |
CCH90168.1 | manA-2 | MODMU_4787 | MODMU_4690 | Putative phosphomannomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Mannose-6-phosphate isomerase, class I; Function of strongly homologous gene; enzyme. | 0.940 |
CCH90168.1 | manB | MODMU_4787 | MODMU_4695 | Putative phosphomannomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.914 |
CCH90608.1 | CCH87902.1 | MODMU_5233 | MODMU_2473 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | 0.947 |
CCH90608.1 | frk | MODMU_5233 | MODMU_2210 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | Sugar kinase, ribokinase; Function of strongly homologous gene; enzyme. | 0.947 |
CCH90608.1 | glpX | MODMU_5233 | MODMU_1056 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | Fructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.750 |
CCH90608.1 | manA-2 | MODMU_5233 | MODMU_4690 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | Mannose-6-phosphate isomerase, class I; Function of strongly homologous gene; enzyme. | 0.928 |
CCH90608.1 | pfkA | MODMU_5233 | MODMU_0037 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.804 |
CCH90608.1 | pfkA-2 | MODMU_5233 | MODMU_3509 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.801 |
CCH90608.1 | pgi | MODMU_5233 | MODMU_4321 | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | Glucose-6-phosphate isomerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. | 0.895 |
frk | CCH87902.1 | MODMU_2210 | MODMU_2473 | Sugar kinase, ribokinase; Function of strongly homologous gene; enzyme. | Ribokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. | 0.915 |
frk | CCH90608.1 | MODMU_2210 | MODMU_5233 | Sugar kinase, ribokinase; Function of strongly homologous gene; enzyme. | PTS system, fructose subfamily, IIC subunit; Function of strongly homologous gene; transporter. | 0.947 |
frk | glmS | MODMU_2210 | MODMU_4874 | Sugar kinase, ribokinase; Function of strongly homologous gene; enzyme. | Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.911 |