STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
bccAAcetyl-/propionyl-coenzyme A carboxylase alpha chain [Biotin carboxylase; Function of strongly homologous gene; enzyme. (587 aa)    
Predicted Functional Partners:
CCH90146.1
Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.998
pccB
Propionyl-CoA carboxylase beta chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.996
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.994
fabD-2
Malonyl CoA-acyl carrier protein transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.991
accB
Acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.988
CCH90147.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 0.987
accD-2
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Function of strongly homologous gene; enzyme.
 0.985
CCH86897.1
Methylcrotonoyl-CoA carboxylase; Function of strongly homologous gene; enzyme.
 
 0.980
ahs
Allophanate hydrolase, subunit2; Function of strongly homologous gene; enzyme.
 
 0.960
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.938
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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