Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase; Function of strongly homologous gene; enzyme. (455 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family.
 
 
 0.998
hemA-2
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
hemD
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
 
 
 0.989
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
cysG
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
 
  
 0.982
gpmB-2
Phosphoglycerate mutase; Function of strongly homologous gene; enzyme.
  
  
 0.970
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.950
CCH87370.1
Alkyl hydroperoxide reductase/ Thiol specific antioxidant; Function of strongly homologous gene; enzyme.
  
  
 0.908
CCH85858.1
Mixed type I polyketide synthase-non ribosomal peptide synthetase; Function of strongly homologous gene; enzyme.
 
  
 0.904
CCH90807.1
Mixed type I polyketide synthase-non ribosomal peptide synthetase; Function of strongly homologous gene; enzyme.
 
  
 0.870
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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