node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCH88643.1 | cobIJ | MODMU_3230 | MODMU_0655 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | 0.616 |
CCH88643.1 | cysG | MODMU_3230 | MODMU_0617 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. | 0.980 |
CCH88643.1 | hemA | MODMU_3230 | MODMU_2514 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.523 |
CCH88643.1 | hemA-2 | MODMU_3230 | MODMU_4995 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.545 |
CCH88643.1 | hemB | MODMU_3230 | MODMU_4992 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family. | 0.840 |
CCH88643.1 | hemC | MODMU_3230 | MODMU_4994 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.989 |
CCH88643.1 | hemD | MODMU_3230 | MODMU_4993 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. | 0.957 |
CCH88643.1 | hemE | MODMU_3230 | MODMU_3908 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.994 |
CCH88643.1 | hemL | MODMU_3230 | MODMU_4991 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Glutamate-1-semialdehyde 2,1-aminomutase; Function of strongly homologous gene; enzyme. | 0.515 |
CCH88643.1 | ribBA | MODMU_3230 | MODMU_3298 | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.430 |
cobIJ | CCH88643.1 | MODMU_0655 | MODMU_3230 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen III synthase HEM4; Function of strongly homologous gene; enzyme. | 0.616 |
cobIJ | cysG | MODMU_0655 | MODMU_0617 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. | 0.992 |
cobIJ | hemA | MODMU_0655 | MODMU_2514 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.608 |
cobIJ | hemA-2 | MODMU_0655 | MODMU_4995 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.608 |
cobIJ | hemB | MODMU_0655 | MODMU_4992 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family. | 0.692 |
cobIJ | hemC | MODMU_0655 | MODMU_4994 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.712 |
cobIJ | hemD | MODMU_0655 | MODMU_4993 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme. | 0.991 |
cobIJ | hemE | MODMU_0655 | MODMU_3908 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.416 |
cobIJ | hemL | MODMU_0655 | MODMU_4991 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Glutamate-1-semialdehyde 2,1-aminomutase; Function of strongly homologous gene; enzyme. | 0.684 |
cobIJ | ribBA | MODMU_0655 | MODMU_3298 | Cobalamin biosynthesis protein cobIJ [Includes: Precorrin-2 C(20)-methyltransferase; Function of strongly homologous gene; enzyme. | Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.447 |