STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH90377.1Conserved protein of unknown function, putative Thioredoxin domain; Homologs of previously reported genes of unknown function. (81 aa)    
Predicted Functional Partners:
nrdJ
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.906
CCH90378.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase; Function of strongly homologous gene; enzyme.
       0.773
msrA
Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.749
sigX
RNA polymerase, sigma-24 subunit, ECF subfamily; Function of strongly homologous gene; enzyme; Belongs to the sigma-70 factor family. ECF subfamily.
       0.657
rex
Redox-sensing transcriptional repressor rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
  
  
 0.630
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.589
hemA-2
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
       0.589
hemD
Uroporphyrinogen-III C-methyltransferase; Function of strongly homologous gene; enzyme.
  
  
 0.587
serB-2
Phosphoserine phosphatase; Function of strongly homologous gene; enzyme.
 
     0.545
hemB
Delta-aminolevulinic acid dehydratase; Function of strongly homologous gene; enzyme; Belongs to the ALAD family.
       0.505
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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