STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
phoUNegative regulator of PhoR/PhoB two-component regulator; Plays a role in the regulation of phosphate uptake. (218 aa)    
Predicted Functional Partners:
pstA
Phosphate transport system permease protein pstA; Function of strongly homologous gene; transporter.
 
  
 0.995
pstB
High-affinity phosphate transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
  
 0.994
pstC
High-affinity phosphate transport protein (ABC superfamily, membrane); Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.953
phoR-2
Two-component Pi level signal transduction regulator, system with PhoB; Function of strongly homologous gene; enzyme.
 
  
 0.946
CCH90432.1
Extra-cellular phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
  
 0.884
phoB-2
Two-component Pi uptake response regulator, system with PhoR (OmpR family); Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
  
 0.839
dusB
tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
    
 0.723
PhoH
Phosphate starvation-inducible protein; Function of strongly homologous gene; transporter.
 
  
 0.720
phoA
Alkaline phosphatase; Function of strongly homologous gene; enzyme; Belongs to the alkaline phosphatase family.
  
  
 0.706
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.692
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.