STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcaB3-carboxy-cis,cis-muconate cycloisomerase; Function of strongly homologous gene; enzyme. (443 aa)    
Predicted Functional Partners:
pcaC
4-carboxymuconolactone decarboxylase; Function of strongly homologous gene; enzyme.
 
 
 0.998
pcaG
Protocatechuate 3,4-dioxygenase alpha chain; Function of strongly homologous gene; enzyme.
 
 
 0.997
pcaH
Protocatechuate 3,4-dioxygenase beta chain; Function of strongly homologous gene; enzyme.
 
 
 0.997
pcaD
3-oxoadipate enol-lactonase; Function of strongly homologous gene; enzyme.
   
 0.976
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.905
CCH87594.1
Homologs of previously reported genes of unknown function.
      0.869
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.861
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SAICAR synthetase family.
  
 
 0.861
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.859
purD
Phosphoribosylamine--glycine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family.
  
 
 0.859
Your Current Organism:
Modestobacter marinus
NCBI taxonomy Id: 477641
Other names: CGMCC 4.5581, DSM 45201, M. marinus, Modestobacter marinus Xiao et al. 2011, Modestobacter sp. 42H12-1, strain 42H12-1
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